Background: Acute heart failure (AHF) exacerbations are a leading cause of hospitalization in the United States. Despite the frequency of AHF hospitalizations, there are inadequate data or practice guidelines on how quickly diuresis should be achieved. Methods: We conducted a pooled cohort study using data from three acute heart failure trials (DOSE, ROSE, and ATHENA-HF). [...]

Background: Acute heart failure (AHF) exacerbations are a leading cause of hospitalization in the United States. Despite the frequency of AHF hospitalizations, there are inadequate data or practice guidelines on how quickly diuresis should be achieved. Methods: We conducted a pooled cohort study using data from three acute heart failure trials (DOSE, ROSE, and ATHENA-HF). [...]

Background: Reduced payments from Medicare related to high rates of hospital-acquired pressure injuries has prompted hospitals to invest in new technologies and strategies to improve wound care and prevention. While many hospitals have increased the purchase of skin care products such as prophylactic dressings, little is known about the association between these products and reductions [...]

Background: Older adults presenting with trauma have worse outcomes than younger adults with similar injury severity. In 2013, the American College of Surgeons Trauma Quality Improvement Program published guidelines that recommended geriatrics consultation (GC) for high-risk older adults. Many trauma centers implemented GC in congruence with these guidelines, but the impact on patient outcomes is [...]

Background: Reduced payments from Medicare related to high rates of hospital-acquired pressure injuries has prompted hospitals to invest in new technologies and strategies to improve wound care and prevention. While many hospitals have increased the purchase of skin care products such as prophylactic dressings, little is known about the association between these products and reductions [...]

Background: Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are commonly-used antihypertensives which, despite renoprotective properties, can contribute to acute kidney injury (AKI)(1). Iodinated contrast media may also precipitate AKI, namely contrast-induced nephropathy (CIN), which has been associated with adverse patient outcomes(1–3). ACE inhibitors and ARBs are often held in the setting of iodinated [...]

Background: Acute kidney injury (AKI) following cardiac surgery occurs in 30% of cases with 1% requiring dialysis resulting in significant morbidity and mortality.  HMG-CoA Reductase Inhibitors (“statins”) have been postulated to be of benefit in this population, however results from existing clinical studies have been inconsistent. Since there is abundance of evidence showing that short-term [...]

Background: Falls are the most common cause of nonfatal trauma-related hospital admissions among older adults. The objective of this study was to determine whether the quarantine/lockdown elicited by the SARS-CoV-2 pandemic led to a change in the incidence of falls in geriatric patients between March 2020 – December 2020 compared to March 2019 – December [...]

Background: Hematopoietic stem cell transplantation (HSCT) remains the only definitive treatment for many benign and malignant hematologic disorders. Despite advances in transplant medicine, HSCT still carries a significant risk of serious complications, including idiopathic pneumonia syndrome (IPS). IPS is characterized by diffuse alveolar injury that is not due to infection or fluid overload. IPS affects [...]

Background: Since the start of the coronavirus disease 2019 (COVID-19) pandemic, millions have succumbed to the infection worldwide. The virus is most well-known for its devastating pulmonary and cardiovascular manifestations, but acute kidney injury (AKI) has been frequent as well (reported incidence ranging from 0.5% to 56.9%), and has been repeatedly observed to be associated [...]