Case Presentation: 46 year old male with history of hypertension on losartan, gastroesophageal reflux disease on omeprazole and history of gout (not on medications) presents to his primary care provider for a new onset skin rash. Examination revealed a non-pruritic, petechial rash on his anterior chest and upper extremities that started 5 days ago. He [...]

Case Presentation: 59 year old man with hypertension initially presented to the hospital with bleeding, oral lesions. They developed four days prior to presentation. They manifested as bullae which eventually “popped” and bled. Patient had no other associated symptoms, including fever, chills, dizziness, chest pain, dyspnea, or irregular bleeding. He works as a city bus [...]

Case Presentation: A 36-year-old healthy woman with no past medical history presented to the emergency department with generalized purpura and petechiae. She also reported 4 month long history of painless right-sided neck swelling, drenching night sweat and unintentional significant weight loss. Her examination revealed bilateral cervical lymphadenopathy and splenomegaly. Labs showed platelets of 5 K/UL [...]

Case Presentation: A 40 year old recently immigrated Indian male with medical history significant for two episodes of hemorrhagic dengue fever presented with a three day history of epistaxis, gingival bleeding, hematuria, hematochezia and a vesicular rash. On presentation, the physical exam was remarkable for a large mucosal hematoma, gingival bleeding, and diffuse hemorrhagic vesicular [...]

Case Presentation: A 65 year-old man with primary antiphospholipid syndrome (APS) was transferred to our hospital for management of refractory thrombocytopenia and thrombosis. His disease was diagnosed by positive lupus anticoagulant, anti-cardiolipin antibody, beta-2-glycoprotein IgM and IgG, and was well controlled with warfarin for years. His worsening APS was precipitated by traumatic subdural hematomas and [...]

Case Presentation: A 27-year old African American male presented with 3 months of bilateral inguinal lymph node enlargement, fevers, night sweats, fatigue, and weight loss. Patient presented for outpatient nodal biopsy and subsequently sent to the ED with severe thrombocytopenia with platelets less than 10,000 and complaints of gum bleeding and petechiae of 3 days. [...]

Case Presentation: A 84-year-old woman with a past medical history of HTN, DM2, CHF, and hypothyroidism presented to an offsite ED after falling on her buttock when rising from a kitchen chair. She had an uneventful course of COVID-19 four weeks prior. Over the last 2 weeks, she developed progressive weakness. Upon arrival at the [...]

Case Presentation: 73-year-old man was diagnosed with immune thrombocytopenia (ITP) in 2011 and was treated with intravenous immunoglobulin (IVIG), high dose steroid, rituximab and romiplostim to which he responded and subsequently was weaned off of azathioprine and steroid and achieved remission starting 2012. Eight weeks after receiving second dose of Pfizer’s BNT162b2 vaccination, he noted [...]

Case Presentation: A 23 year-old previously healthy woman presented with a 2-day history of melena, hematemesis, vaginal bleeding, and bleeding gums. She also reported cough, fevers and anosmia. She denied any new medication exposures and had no prior history of bleeding disorders or hematologic disease. Temperature was 37.2° C, heart rate 122, respiratory rate 18, [...]

Case Presentation: A 28 year-old unvaccinated man with a history of Hodgkin’s lymphoma in remission presented with thrombocytopenia. Six weeks ago, he was exposed to COVID-19 and developed cough and rhinorrhea. He was not tested but started taking hydroxychloroquine and azithromycin. Three weeks prior to admission, he began noticing mucosal bleeding. One week prior to [...]