Background: Stroke is one of the most common causes of adult mortality. With changes in lifestyle, the increase in risk factors is leading to an increase in the number of cases. Mean platelet volume (MPV) is associated with an increase in platelet size and hence increased production of pro-inflammatory cytokines and increased expression of platelet [...]

Background: Lumbar Punctures (LPs) are generally considered to be safe bedside procedures, but when bleeding complications arise they can be catastrophic with epidural hematomas risking spinal cord compression and paralysis if untreated. Our institution serves a large number of patients with hematologic malignancies requiring intrathecal chemotherapy, sometimes as frequently as twice weekly, who often have [...]

Case Presentation: 55 year old man with history of diabetes, hypertension and remote history of testicular cancer treated with chemotherapy and orchiectomy in 1993 and currently with no active malignancy presents with fever and malaise which began about a week ago. On admission, his laboratory results were notable for leukocytosis with a white blood cell [...]

Case Presentation: A 3-month-old male of Asian descent with a past medical history of congenital CMV and right-sided sensorineural hearing loss presented to the ED with two days of GI bleeding tendencies, easy bruising, and diffuse rash. The patient was otherwise healthy with normal appetite and vital signs. He had no falls, traumas, or sick [...]

Background: Current guidelines recommend continuing aspirin during elective non-cardiac surgery in 1) patients with prior percutaneous coronary intervention (PCI) if the bleeding risk allows and 2) patients without prior PCI if thrombotic risk outweighs bleeding risk. Comparing the risk of thrombosis and bleeding is frequently inexplicit, particularly in low and intermediate bleeding risk surgery. The [...]