Case Presentation: A 30-year-old man with sickle cell anemia presented to the ED with pain in his left hip similar to prior vasooclussive crisis (VOC). There was no identifiable trigger and his review of symptoms was negative. Past medical history included sickle cell anemia complicated by acute chest syndrome (ACS), avascular necrosis of the right [...]

Background: Hydroxyurea is an FDA approved medication for use in adults with sickle cell disease. Clinical guidelines, based on high quality evidence, recommend its use in all adults with sickle cell anemia and 3 or more moderate to severe pain crises within one year.  Studies suggest its use to be inappropriately low. We assessed local [...]

Background: Sickle cell crisis is a acute medical emergency, which may require management in the ICU. Sickle cell anemias are remarkable in their clinical heterogeneity. Some people remain asymptomatic in their adult life, whereas others suffer repeated crisis; requiring multiple hospitalizations. In this study, we determine the demographic factors associated with a high readmission rate [...]