Background: Skin, soft tissue, and joint infections are common in pediatric patients and can require invasive procedures to drain purulent fluid. Atypical pathogens (fungal and acid-fast bacilli [AFB]) are important but rare causes of these infections with reported case rates as low as 0.6-1.6 cases/100,000 a year. Despite the rarity of these infections, costly atypical [...]

Background: Despite detailed Infectious Disease Society of America (IDSA) skin and soft tissue infection guidelines, patients with cellulitis at our institution consistently receive antibiotics with high local resistance or that are inappropriate based on IDSA guidelines. Our baseline data showed that 55 percent of patients receive antibiotics per IDSA guidelines and only 33 percent of [...]

Case Presentation: A previously healthy and ambulatory 34-year-old diabetic man presented with left-sided scrotal and groin cellulitis and was admitted to the hospital for intravenous antibiotic therapy. He was placed on appropriate pharmacoprophylaxis for venous thromboembolic disease and was observed ambulating on the unit. Despite one week of appropriate antibiotic therapy, he continued to have [...]

Case Presentation: A 69-year old male with past medical history significant for granulomatosis with polyangiitis and lower extremity deep vein thrombosis (DVT) presented with worsening pain, swelling and erythema of his right lower extremity. He reported exposure to stagnant rainwater in his yard a day prior to admission. Hours after the exposure he developed fever [...]

Case Presentation: A 76-year-old female noted left fourth- and fifth-digit pain on day 12 receiving trimethoprim/sulfamethoxazole (TMP/SMX) and linezolid for purulent collections of Nocardia abscessus complex in the right gluteal and paraspinal muscles. She had a medical history of atrial fibrillation on apixaban, heart failure with preserved ejection fraction, and a history of deceased donor [...]