Case Presentation: A 25-year-old Black transgender woman receiving cross-sex hormone therapy (CSHT) with a PMH of multiple hospitalizations for HbSS sickle cell disease (SCD) complicated by acute chest syndrome, chronic left upper extremity DVT, and painful vaso-occlusive crises (VOC) was admitted for acute back and leg pain. She described the pain as constant, sharp, 10/10 [...]

Case Presentation: A 29 year-old woman with sickle cell disease (SCD) on hydroxyurea and L-glutamine, and mild intermittent asthma presented to our institution with right lower extremity and back pain suggestive of a vaso-occlusive crisis. She did not report fever, cough or dyspnea. Vital signs revealed a heart rate of 91/min, blood pressure of 126/86 [...]