Case Presentation: The diagnosis of a sexually active young male who presents with fevers, night sweats, weight loss with opportunistic infections and then found to have an acquired immunodeficiency is going to be HIV except when it isn’t. We present a patient with a presumptive diagnosis of HIV but a negative comprehensive HIV laboratory testing [...]

Case Presentation: Idiopathic CD4 lymphocytopenia (ICL) is a disease characterized by persistently low CD4 T-cell counts without HIV infection or any other discernible cause of T-cell suppression. Individuals with ICL are at increased risk of opportunistic infections, lymphomas, and autoimmune diseases. Diagnosis can be difficult, and prognosis can vary widely depending on the diseases that [...]