Case Presentation: A 49-year old man with no significant medical history presented with dyspnea and presyncope. He presented similarly six weeks prior and was diagnosed with constrictive pericarditis thought to be of a viral etiology. He had reported an eighteen-kilogram weight loss, intermittent fevers, and night sweats, but, given clinical improvement, was discharged on ibuprofen [...]

Case Presentation: A 19-year-old male in the United States Marine Corps (USMC) presented with severe fatigue and an inability to complete a 15-mile march. His initial hemoglobin (HgB) level was 2.5 g/dL, and his mean corpuscular volume (MCV) was elevated at 131.6 fL. After receiving 4 units of packed red blood cells, his HgB improved [...]

Case Presentation: A 75 year-old man with no significant history presented with four weeks of malaise and lower extremity rash, five days of cough and rhinorrhea, and one day of pleuritic chest pain that he attributed to incessant coughing. On arrival he was febrile to 38.3 Celsius and tachycardic to 120 beats per minute. His [...]

Case Presentation: A 64-year-old man presented with persistent anemia, weight loss, fatigue, fever, cough, episcleritis, chondritis, and facial pain. Initial investigations highlighted macrocytic anemia and elevated alkaline phosphate. Despite initial suspicion of a streptococcal infection and subsequent treatment with antibiotics, his condition did not improve. Further evaluation revealed cavitary nodules on chest imaging, with biopsies [...]

Case Presentation: A female patient was referred to hematology/oncology with severe neutropenia and leukopenia. Bone marrow biopsy revealed ringed sideroblasts with multilineage dysplasia consistent with MDS. Further diagnostic workups did not reveal common genetic mutations, and she was scheduled to start treatment with either erythropoietin or luspatercept. Copper deficiency was later found in follow-up, which [...]