Background: Syphilis cases in the United States increased by 28.6% between 2020 and 2021. San Francisco was the highest-risk county for early syphilis in 2017, and between 2017 and 2021, syphilis diagnoses further increased by 12%, with a 200% increase in syphilis cases among women and a 333% increase in congenital syphilis cases compared to [...]

Background: Patients with substance use disorders (SUDs) are at high risk for blood borne viruses (BBV) and sexually transmitted infections (STIs).1 Syphilis infections, in particular, have dramatically increased over the past decade. More patients with syphilis infections are reporting injection drug use.2 Hospitalization is considered a “reachable moment” for this vulnerable patient population.3 Yet, screening [...]

Case Presentation: A 30-year-old man presented for evaluation of multiple episodes of recurrent non-bloody, watery diarrhea and abdominal complaints. Initially seen in clinic, he was well appearing, with normal lab work (CBC, BMP, TSH, TTG IgA, CRP), but given the subacute timeframe of his diarrhea (2-3 weeks) he was referred to a gastroenterologist. Further testing [...]