Case Presentation: A 71-year-old man presented with 1 week of progressive fatigue and weakness. Upon arrival, he stated that he could not get out of bed, even to use the bathroom. Notably, he had undergone an infusion of carboplatin, pemetrexed, and pembrolizumab for treatment of lung adenocarcinoma 9 days before presenting. He attributed his symptoms [...]

Case Presentation: A 96-year-old male with a history of type 2 diabetes mellitus, hypertension, coronary artery disease, and recurrent skin malignancies (melanoma and squamous cell carcinoma) presented with acute epigastric abdominal pain radiating to the back accompanied by nausea and anorexia. He had two previous episodes of similar presentation at another healthcare facility. His recent [...]

Case Presentation: A 70-year-old man with a history of stage III melanoma, previously treated with surgical resection and pembrolizumab, presented with diplopia and ptosis. Laboratory results showed significantly elevated high-sensitivity troponins and creatine kinase-MB. Initial electrocardiogram revealed complete atrioventricular block without ST-segment changes, necessitating the placement of a transvenous pacemaker. Echocardiogram showed an ejection fraction [...]

Case Presentation: We present a case of early and atypical checkpoint inhibitor pneumonitis (CIP) in an elderly female with chronic obstructive pulmonary disease (COPD) who received just two infusions of Pembrolizumab for stage III non-small cell lung carcinoma (NSCLC). Before starting immunotherapy, she had been receiving chemotherapy with carboplatin and paclitaxel for 6 months. The [...]

Case Presentation: 75-year-old female with a past medical history of triple negative breast cancer, Stage IIB, undergoing adjuvant radiation therapy, on cycle 3 of pembrolizumab, presented with fatigue and myalgia. On Day 1, she was found to have hyponatremia with a sodium level of 125 mmol/L, urine osmolality of 227 mOsm/kg, and urine sodium of [...]