Meeting
Abstract Number: 22
SHM Converge 2024
Background: Among patients undergoing cardiac surgery on cardiopulmonary bypass (CPB), post-operative complications are common, occurring in up to 67% of patients, and significantly impact long-term outcomes. We conducted a Phase 2 clinical trial of RBT-1, a pharmacologic preconditioning drug, to assess cytoprotective biomarkers and clinical outcomes. Herein, we report our final results. Methods: This randomized, […]
Abstract Number: 186
SHM Converge 2024
Background: Patients undergoing cardiac surgery are at risk of anemia from blood loss, inflammation, and red blood cell lysis, necessitating blood product utilization and increasing the risk of post-operative complications. RBT-1 (a combination of stannic protoporfin and iron sucrose) is a novel preconditioning drug administered prior to surgery that upregulates anti-inflammatory, antioxidant, and iron scavenging […]