Background: Tumor necrosis factor-α (TNF-α) plays a role in the pathogenesis of and serves as a biomarker for obstructive sleep apnea (OSA) [1]. Moreover, patients with juvenile idiopathic arthritis (JIA) had a numerically elevated risk of OSA [2-4]. Given TNF-α inhibitors have been widely used to treat JIA, the aim of the present study was [...]

Background: Rhabdomyosarcoma (RMS) is an exceptionally rare soft tissue sarcoma that exhibits significantly lower survival rates in adults when compared to pediatric patients. This disparity is likely attributed to a combination of histopathological variations, delayed, or missed diagnoses, and treatment-related factors(1). Notably, adult RMS originating from the extremities is classified as “unfavorable” and has been [...]

Case Presentation: We present a 37-year-old man with refractory hypokalemia hospitalized for resection of his sarcoma sacral lesions. History was also significant for biopsy proven mucormycosis thyroid infection three months prior with the additional finding of a right lower lobe cavitating consolidation. He underwent subsequent thyroidectomy and was initially treated with amphotericin B and posaconazole [...]

Case Presentation: A 72 year old diabetic male presents to the hospital with a severe and extensive rash involving the entire body. Despite being treated with prednisone, topical steroids and doxycycline, the patient’s symptoms worsened and spread cephalocaudally, eventually spreading to the hands and bilateral lower extremities. Skin biopsy confirmed a diagnosis of Pityriasis Rubra [...]

Case Presentation: A 75-year-old man with recurrent well-differentiated liposarcoma on Palbociclib s/p multiple tumor resections and recent cryoablation of a right retrocaval lesion 6 weeks prior, presented with 5 weeks of worsening right flank pain, decreased appetite, and 25-pound unintentional weight loss. He was afebrile with normal vitals. He had petechiae on his palate. Labs [...]

Case Presentation: Ghosal hematodiaphyseal dysplasia (GHDD) is a rare autosomal recessive disorder presenting with myelophthisic anemia and distinctive bony changes. TBXAS1 gene encodes Thromboxane A synthase. In GHDD, dysregulation of TBXAS1 occurs and this increases prostaglandin synthesis and causes direct bone marrow injury. Here we report, a 31-year-old Southeast Asian female presented with bilateral knee [...]