Case Presentation: Hypokalemia, especially serum potassium concentrations of < 2.5 mmol/L, is a well-recognized etiology of generalized muscle weakness. While hypokalemia, weakness, and thyroid disorders are common clinical entities, thyrotoxic periodic paralysis (TPP) is a rare condition driven by both increased gene transcription and increased intrinsic activity of the Na-K-ATPase pump. Here, we present a [...]

Case Presentation: A 46 year old man living in southwestern Maine with a history of hypertension, hyperlipidemia, and obesity presented in late September with 2 days of numbness in the right foot that progressed to bilateral lower extremity weakness, numbness, and difficulty ambulating. Patient denied any recent illnesses, vaccinations, travel or known bites the month [...]

Case Presentation: A twenty-year-old male patient with no past medical history presented to the emergency department with bilateral lower extremity weakness after working in agricultural fields which had progressed over three hours to near paralysis. When the patient was first evaluated, an ECG revealed his heart rhythm to be in asymptomatic ventricular tachycardia. He exhibited [...]

Case Presentation: An 18-year-old male presented with ascending paralysis, starting in the lower extremities and progressing to the upper extremities over 24 hours after a carbohydrate rich meal. Other review of systems was negative. He reported one prior ICU admission for similar symptoms, but details were not available. Father and grandfather had similar presentations of [...]