Background: The direct oral anticoagulants (DOACs) apixaban and rivaroxaban are increasingly prescribed due to convenient oral formulation without the need for routine laboratory monitoring and are now commonly regarded as first line anticoagulants in most cases of venous thromboembolism (VTE). However, the optimal choice of subsequent anticoagulant in instances of first line DOAC failure is [...]

Background: Venous thromboembolism (VTE) is a leading cause of preventable in-hospital mortality and a primary focus of quality improvement/patient safety efforts. VTE prophylaxis reduces the incidence of in-hospital VTE, but nonadministration rates—primarily attributed to patient refusal—often reach 10-15%. Notably, nonadministration of VTE prophylaxis may correlate with higher incidence of hospital acquired VTE. Prior studies showed [...]

Case Presentation: Case 1: A 38-year-old woman with no past medical history presented to the hospital with four days of fatigue, myalgias, and productive cough. On admission, she was febrile to 103 F, had a heart rate of 130 with ECG showing sinus tachycardia, saturating 95% on two liters of nasal cannula oxygen. Initial workup [...]