Case Presentation: A 57 year old man with a history of heart failure with preserved ejection fraction (HFpEF), chronic kidney disease (CKD) and hypertension presented with two weeks of exertional dyspnea and lower extremity edema, followed by 4-days of progressive tongue swelling. One-month prior, he was initiated on an ACE inhibitor (ACEi) and experienced tongue [...]

Case Presentation: A 24 year old Afro-Caribbean woman with no medical history presented with intermittent facial swelling of one month, several months of fatigue, anorexia and unintentional weight loss of 65 pounds. The swelling initially involved the lower face with gradual spread to bilateral peri-orbital areas. There was no urticaria, rash, dysphagia, dyspnea or visual [...]