Background: Recent data suggest that there are mortality benefits from preoperative statin therapy in patients at high risk for atherosclerotic cardiovascular disease (ASCVD). Current guidelines recommend moderate or high intensity statin for all patients with established ASCVD or 10-year risk of > 7.5%. In our preoperative evaluation clinic which is staffed by hospitalists, there were [...]

Case Presentation: Statin-induced necrotizing autoimmune myopathy (SINAM) is an immune mediated myopathy characterized by proximal muscle weakness and necrosis in the presence of autoantibodies to hydroxyl-methyl-glutaryl-coenzyme-A (HMG-CoA) reductase. It is a rare side effect of statin use that must be recognized quickly in order to prevent the development of irreversible muscle weakness. Most cases occur [...]

Case Presentation: A 75-year-old Caucasian female with a history of hyperlipidemia treated with statin presented to the emergency room for generalized weakness. She became completely bedbound over the course of 5 days. Examination showed symmetric muscle weakness with power 2/5 at proximal muscles but normal strength in distal muscles. Deep tendon reflexes were decreased. She [...]