Case Presentation: A 62 year-old woman with hypertension presented with one day of profound, generalized weakness. The patient awoke from sleep and felt nearly paralyzed from the neck down, unable to walk or hold a glass of water. Exam revealed 2+ strength in upper and lower extremities and left wrist drop but no cranial nerve [...]

Case Presentation: A previously healthy 4 year-old male presented with bilateral leg pains and abnormal gait for 3 days. One week prior to admission, the patient had viral upper respiratory symptoms consisting of dry cough, congestion and rhinorrhea without abdominal pain or diarrhea, which resolved prior to presentation. Three days prior to presentation he began [...]

Case Presentation: A 29-year-old Asian male with a one-year history of recurrent generalized muscle weakness presented to the emergency department with whole body paralysis. The patient’s symptoms began abruptly that morning, when he was unable to stand and exit a train due to lower extremity weakness, which generalized over the course of one hour. He [...]

Case Presentation: Statin-induced necrotizing autoimmune myopathy (SINAM) is an immune mediated myopathy characterized by proximal muscle weakness and necrosis in the presence of autoantibodies to hydroxyl-methyl-glutaryl-coenzyme-A (HMG-CoA) reductase. It is a rare side effect of statin use that must be recognized quickly in order to prevent the development of irreversible muscle weakness. Most cases occur [...]