Background: The role of aspirin in primary prevention of cardiovascular events remains controversial, Especially in diabetic patients. We have conducted a meta-analysis of all randomized controlled trials (RCTs) to evaluate the efficacy and safety of aspirin for primary prevention in diabetic patients. Methods: Literature search of Pubmed, MEDLINE, Cochrane Library and Clinicaltrials.gov for related RCTs [...]

Background: Antipsychotics are frequently used in the hospital setting for managing both acute and chronic psychiatric disorders. However, antipsychotics have been associated with higher rates of mortality due to their cardiovascular risk factors, such as QT prolongation. This study aimed to determine the association between cumulative dose of antipsychotics (first and second-generation) and QT prolongation, [...]

Background: Education is one of the determinants of health as described by the WHO, and it is one of the primary determinants of Socio-Economic Class (SEC), a higher level of education is associated with a higher level of SEC. Few researchers have addressed the link between the level of education and cardiovascular disease. However, there [...]

Background: Clinical practice guidelines (CPG) are a constructive response to the clinical situations providing systematically developed statements that include recommendations intended to optimize patient care. Despite their value, inadequate dissemination and implementation of the CPGs derail quality improvements in patient care. Traditionally, static documents (PDF, HTML pages) have been used to deliver CPGs incorporated into [...]

Background: Hypertension is a significant risk factor for cardiovascular disease. According to the Centers for Disease Control and Prevention (CDC) half of all United States citizens with hypertension (HTN) do not have their blood pressure under control. As such, HTN remains a large public health challenge, especially in patients with other comorbidities such as diabetes [...]

Background: Guidelines recommend in-hospital evaluation with cardiac monitoring and transthoracic echocardiogram (TTE) to assess syncope in patients that are considered high-risk for major adverse cardiovascular events. We sought to identify variables associated with performing TTE in patients presenting with syncope. Methods: We abstracted demographic and clinical data from all patients evaluated for syncope at the [...]

Background: Emergency medicine doctors should take care of patients with a wide range of illnesses at various emergency levels from non-urgent level to that requiring immediate medical attention. Among those, cardiovascular emergencies are not so common but life-threatening disorders that must be recognized immediately to avoid delay in treatment and to minimize morbidity and mortality. [...]

Case Presentation: A 60-year-old female with history of a hip replacement complicated with MRSA s/p multiple revisions and sick sinus syndrome with pacer placed in 2004, presented to the ED with an “itchy rash most tender at the pacemaker site” where a cardiovascular implantable electronic device (CIED) within a TYRx envelope was placed two days [...]

Case Presentation: A 64-year-old woman with a history of heart failure (HF) and end stage renal disease on dialysis presented with three days of abdominal pain. She was lethargic, hypothermic to 34.5 C, with jugular venous pulsations (JVP) to the earlobe, a systolic murmur at the left sternal border, and right upper quadrant tenderness. Laboratory [...]