Case Presentation: A 4-year-old presented with persistent fever, headache and vomiting. History was significant for a 5 day febrile illness 1 month earlier and a family history positive for late-onset rheumatoid arthritis in a maternal grandparent. Parents reported that 4 days following resolution of the illness, his fever (up to 104F) recurred and persisted daily [...]

Case Presentation: A 71 year-old man with no medical history presented in October with fevers, headache, neck stiffness, photophobia, and confusion for 3 days. Per family, patient was fully functional with no memory deficits at baseline. He never traveled outside of New York tri-state area and has had no sick contacts or insect bites. Initial [...]

Case Presentation: A 63 year old female with metastatic melanoma to brain and breast presented to the emergency department with altered mental status. She was disoriented to time and place and unable to follow commands. She had received two doses of immunotherapy with ipilimumab and nivolumab. Her last dose was administered two weeks prior. She [...]

Case Presentation: A 51-year-old African female with 7-year untreated HIV infection presented with sudden-onset acute psychosis. She was agitated and reported auditory hallucinations upon arrival. On exam, she was hemodynamically stable but appeared drowsy, intermittently following one-step commands. She did not have meningismus or focal neurological deficits. Physcial exam of other systems was unremarkable.CBC and [...]

Case Presentation: We present a previously healthy 22-year-old female presenting with disorganized behaviors, restlessness and sub-acute decline in mental status. There was no other relevant medical, personal or familial history. However, she had stressors three days before initial change in behavior, such as infidelity with her significant other and she had tremendous anxiety and guilt [...]