Case Presentation: A 69 year-old male with widely metastatic melanoma presenting seven weeks into his treatment with ipilimumab and nivolumab with five days of progressive lightheadedness, headache, nausea, non-bloody emesis, and generalized malaise. The patient had witnessed syncope in the clinic and was sent to the emergency room where he was febrile to 100.8 and [...]

Case Presentation: A 63 year old female with metastatic melanoma to brain and breast presented to the emergency department with altered mental status. She was disoriented to time and place and unable to follow commands. She had received two doses of immunotherapy with ipilimumab and nivolumab. Her last dose was administered two weeks prior. She [...]

Case Presentation: A 55 year old male with metastatic lung cancer presented to the emergency department with right arm pain, weakness and right hand numbness. Patient had brain metastasis previously treated surgically and with radiotherapy. His last treatment with radiation was to the left cerebellum, 3 months prior. Patient was started on pembrolizumab and vorinostat [...]

Case Presentation: A 71-year-old man with metastatic melanoma on pembrolizumab, presented with loss of appetite, nausea, vomiting, fatigue, and lightheadedness over the preceding three weeks. He was found to have orthostatic hypotension with dry mucus membranes on physical exam. Laboratory investigation revealed a sodium of 121 mmol/L. An 8am cortisol was checked and found to [...]

Case Presentation: A 77 year old man with adenocarcinoma of the lung s/p chemotherapy and radiation presented to the Orthopedics service with hip pain & a left femoral lytic lesion.Soon after his IR-guided femur biopsy, medicine consult was called for ? cellulitis. Patient had new left 2nd toe pain, ankle pain, & knee pain, with [...]