Background: Patients (pts) with congestive heart failure (CHF) are at an increased risk for community-acquired bacterial pneumonia (CABP) [1]. Moreover, CABP itself and macrolide antibiotics, which current guidelines recommend for CABP treatment [2], are both associated with increased risk of cardiac events, including worsening heart failure [3,4]. Lefamulin (LEF) is a first-in-class systemic pleuromutilin antibiotic […]

Background: Congestive heart failure (CHF) is a major cause of mortality and morbidity among general population despite recent advancements in goal-directed therapies. The advent of mechanical circulatory devices, the increased availability and improvement in heart transplant techniques have improved some metrics; however, CHF patients continue to have multiple readmissions for acute exacerbations. The frequency of […]

Case Presentation: A 73 year-old man with type 2 diabetes mellitus (hemoglobin A1c 7.5), hypertension, hyperlipidemia, chronic renal failure stage 3a, and a distant 10 pack year smoking history presented with 2 weeks of substernal chest tightness and dyspnea on exertion. He was hemodynamically stable without tachypnea at rest. Examination revealed a grade 2/6 holosystolic […]