Background: Mitochondrial disease (MD) refers to a group of clinically heterogeneous disorders that result from dysfunctional oxidative phosphorylation and subsequent cellular incapability to meet energy demands. Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), myoclonus, epilepsy, ataxia with ragged red fibers (MERRFs), chronic progressive ophthalmoplegia, Kearns–Sayre syndrome, and sensory ataxia neuropathy dysarthria ophthalmoplegia are among [...]

Background: Postmyocardial Infarction Syndrome (PMIS), also called Dressler syndrome or Post-pericardiotomy Syndrome, refers to a heterogeneous group of autoimmune-mediated conditions of pericardial, epicardial and myocardial inflammation following myocardial infarction. Generally considered to be rare in the reperfusion era, the features and risk factors of PMIS are less well characterized in the contemporary era. This study [...]

Background: The obesity paradox describes a counterintuitive observation of improved outcomes in patients with obesity. Analysis of the association among overweight/obesity and leading causes of inpatient mortality in a systemic manner has not been conducted. Methods: We used STATA (StataCorp, College Station, Texas) to analyze the 2016 National Inpatient Sample (NIS). We recognized patients with [...]

Case Presentation: A 70-year-old woman was admitted to our medical center with a 2-month history of abdominal discomfort, anorexia and fatigue. Past medical history was notable for hyperlipidemia. Five weeks prior to admission, the patient presented to her primary provider with similar complaints and was found to have significantly elevated liver enzymes, as shown in [...]

Case Presentation: A 22-year-old female with a history of biopsy-proven eosinophilic esophagitis, gastroparesis, multiple food allergies, and intermittent amenorrhea presented to the emergency room with weakness and lightheadedness. In the past month she experienced a 15lb weight loss, early satiety, and increasing fatigue. She was being followed outpatient by a gastroenterologist for several months of [...]