Background: Patients admitted to New Hanover Regional Medical Center with a history of opiate use disorder (OUD) and serious infections require a median length of stay (LOS) of 33 days and discharge against medical advice (AMA) 26% of the time, resulting in quality and safety gaps which includes incomplete treatment, readmissions, and high cost of [...]

Background: Orbital cellulitis/abscess (OC) is an infection of eye tissues posterior to the orbital septum. OC can have significant morbidities such as vision loss, cavernous sinus thrombosis, and intracranial infection if treatment is not initiated promptly. While some patients with orbital cellulitis complicated by subperiosteal abscess require surgical drainage, many are managed with intravenous (IV) [...]

Case Presentation: AS is 36-year-old woman with methamphetamine and opioid use disorder (OUD) hospitalized with endocarditis who is evaluated by the Addiction Consult Service (ACS), and started on sublingual Buprenorphine/naloxone (Bup/nx) for treatment of OUD. Urine drug screens continue to be inappropriately positive for methamphetamine inpatient. Extended Release Buprenorphine (Bup-XR) is discussed and with her [...]