Case Presentation: A 17 y.o. female with systemic lupus erythematosus (SLE) presented with several weeks of worsening migratory polyarthralgia, as well as sporadic fevers, night sweats, and chills. Prednisone was begun 3 weeks prior for a presumed SLE flare, given elevated anti double-stranded DNA (anti-dsDNA) and erythrocyte sedimentation rate (ESR) and hematuria, but provided no [...]

Case Presentation: Schnitzler syndrome (SD) is a rare auto-inflammatory disease where patients present with recurrent fevers, arthralgias, urticaria, monoclonal gammopathy and elevated inflammatory markers. It was first described by Liliane Schnitzler in 1972 [1]. Given the complexity and rarity of this syndrome it is often underdiagnosed and causes a significant delay between disease onset and [...]

Case Presentation: A previously healthy 13-year-old female presented to a pediatric emergency department with 5 days of abdominal pain, emesis, headache, arthralgia, and fever. Vital signs included temperature of 100.2 F, heart rate of 122 beats/minute, normal blood pressure for age, and oxygen saturation of 99% on room air. She was ill appearing with bilateral [...]

Case Presentation: A 19-year-old woman with a history of anxiety was admitted to the hospital with one week of fever to 103 degrees F, sore throat, fatigue, and severe arthralgias. History was notable for pleuritic chest pain, an intermittent rash over her arms and thighs, and a 23-pound weight loss over 12 months, which she [...]

Case Presentation: A 38-year-old woman with a history of discoid lupus presented with a week of progressive fever, chills, pustular rash, and polyarthritis. The pustular lesions started periorally but then spread to the palms, soles, and torso. Her joint pain was predominantly in her ankles, knees, wrists, and shoulders. Aside from minor scratches from pet [...]