Background: An average of 10% of patients in the U.S. report having a penicillin allergy yet the Centers for Disease Control estimates that less than 1% of the population are truly allergic. It is well described in adult literature that broad spectrum antibiotics are often used as penicillin alternatives and this may contribute to negative [...]

Background: Penicillin class antibiotics are the most frequently reported drug allergy in the electronic health record (EHR), but recent studies find

Background: Over 32 million patients in the United States have a penicillin (PCN) allergy label in their medical chart.1 Studies have demonstrated that 15-20% of hospitalized patients are labeled PCN allergic. However, IgE-mediated PCN allergy wanes over time and up to 80% of patients with a listed PCN allergy can tolerate PCN after 10 years. [...]