Background: Triple negative breast cancer (TNBC) comprises of approximately 15% of the total breast cancers. There is limited data on treatment outcome of these patients in elderly population. We report our experience with elderly patients with TNBC treated at our tertiary care center. Methods: With IRB approval, the Cleveland Clinic’s database was used to identify [...]

Background: Use of Percutaneous Endoscopic Gastrostomy (PEG) tubes among patients with dementia is controversial, with multiple studies showing no clear benefit in terms of risks of aspiration, survival or quality of life. Despite this growing evidence, studies analyzing the trends of use of PEG tube among demented patients are lacking. We aimed to use a [...]

Background: Observation units are a growing destination for many patients with a variety of diagnoses.  The elderly represent a large part of the observation population, which will likely grow as baby-boomers age.  Those of advanced age can have different medical and social needs than their younger cohort, so understanding their prevalence and expected outcomes in [...]

Background: It is known that more people die during the nighttime compared to daytime in the community setting. Many health care providers are required to care for patients in a critical condition which includes around the time of death, and which may be at night. However, there have been few studies with respect to the [...]

Background: Atrial fibrillation (AF) is strongly age-dependent, and with a growing geriatric population, the incidence and prevalence of AF is expected to increase in the United States. As a result, the number of patients at risk of a thromboembolic event due to AF is also expected to increase. Although bleeding associated with mechanical falls is [...]

Background: While delirium may affect patients of any age, delirium prevention and management protocols have focused mostly on the elderly, as older adults (>65 years old) are more vulnerable to developing delirium. Delirium has been reported in 19-31% of younger adults during their hospital stay, and 15-56% of older adults.There is lack of literature on [...]

Background: Aging is associated with increased prevalence of atrial fibrillation and thrombophlebitis. Anticoagulation has been shown to be effective in preventing thromboembolic events in AF patients and treatment of thrombophlebitis. Non-vitamin k antagonist oral anticoagulants (NOACs) have been shown to be non-inferior or even superior to warfarin for long-term stroke prevention and thrombophlebitis treatment. In [...]

Background: The number of elderly stage IV cancer patients is increasing every year. Various factors need to be considered for systemic cancer treatment in older patients. This study was conducted to examine the difference in clinical features and overall survival between the group that received the best supportive care and the group that received active [...]

Background: Hospital-acquired delirium is a common cause of increased morbidity and mortality. In an earlier pilot study, we identified through surveys that adult medicine inpatients slept an average of 4 hours. Also, multiple factors including environmental noise, vital sign checks, and lab draws were recognized as barriers to sleep. Based on this information and prior [...]

Background: There is limited data on the predictors of outcomes in patients who have in-hospital cardiac arrest. This study aims to understand the factors that might affect the survival from the cardiac arrest and survival-to-discharge after in-hospital cardiac arrest. Methods: Institutional review board of the Cleveland Clinic approved the retrospective cross-sectional study for patients who [...]