Background: Epidemiology of Non-Variceal Upper Gastrointestinal Bleeding (NVUGIB) such as peptic ulcer bleeding, Mallory-Weiss tear, erosive gastritis/duodenitis, oesophagitis/oesophageal ulcer is well known among general population. However, data is lacking about its trend among Cirrhotic population in literature. No large database study is available to compare prevalence, predictors, and outcomes of NVUGIB among Cirrhotic patients. We [...]

Background: Hepatic artery pseudoaneurysm (HAP) is a rare entity, potentially life threatening and associated with high mortality. The aim of this study was to evaluate Mayo Clinic enterprise’s clinical experience with HAP occurrence, clinical features and outcome in the last 20 years, and to compare our results with what the literature. Methods: This retrospective analysis [...]

Background: Over the last two decades concerns have been raised about the potential risk of blood transfusion over the benefits. General restrictive red blood cell (RBC) transfusion approach for anemic hospitalized patients (thresh hold of 7 gm %) has been adopted by American hematology society (AHS) in 2012. It is important to recognize that guidelines [...]

Background: Unplanned readmissions among cancer patients are common and gastrointestinal (GI) cancer has some of the highest readmission volumes. Under the Affordable Care Act, hospitals have been getting penalized for excessive readmission rates. For now, the medical treatment of cancer is exempt from this measure. This is because the readmission profile of the cancer patient [...]

Background: Widespread use of new oral anticoagulants (NOAG) for Atrial Fibrillation (A-Fib) has increased the annual incidence of gastrointestinal bleed (GIB) in recent years. These NOAG agents in our study include Rivaroxaban, Apixaban and Dabigatran. Convenience of use, quick onset, broad therapeutic window and eliminating need for frequent monitoring makes NOAGs attractive for A-Fib associated [...]

Background: Given its ability to identify obscure bleeding at a rate of 0.1-0.5 mL/min, technetium-labeled red cell scans have long been considered the most sensitive radiographic test for gastrointestinal bleeding. They are routinely compared to computed tomography angiography, which detects bleeding at a minimum rate of 0.5 mL/min or greater. We conducted a clinical quality [...]

Background: UGIB is a common cause of inpatient admissions often associated with morbidity and an overall mortality rate approaching 10%. Since therapy is different, it is important to differentiate between variceal and non-variceal GI bleeding. While both will often need volume resuscitation, proton pump inhibitors (PPI), judicious transfusion and early endoscopy, patients with variceal bleeding [...]

Background: Infectious gastroenteritis is a common cause of morbidity and mortality worldwide. The FilmArray GI panel (GIP) is a multiplex PCR assay that can rapidly detect 21 gastrointestinal pathogens, including 13 bacteria, 5 viruses, and 4 parasites. The GIP has high sensitivity and specificity for most targets and has been widely adopted in clinical practice. [...]

Case Presentation: A 67 year old woman presented with right upper quadrant abdominal pain and was diagnosed with acute cholecystitis. She underwent elective cholecystectomy, complicated by Clostridium difficile colitis. Despite treatment with oral Vancomycin, she had persistent diarrhea and failure to thrive for a month. Repeat Clostridium difficile toxin was negative. Esophagogastroduodenoscopy showed erosive gastritis [...]

Background: The “weekend effect” is a term to define worse outcomes among patients that present to the hospital on weekends. For upper gastrointestinal bleed (UGIB) some of these outcomes include increased mortality and increased length of stay (LOS). A 2018 meta-analysis suggests that mortality is higher for non-variceal bleed than for variceal bleed for weekend [...]