Case Presentation:       A 33 year-old Hispanic male without significant history presented with an unremitting fever for 5 days, associated with myalgais, fatigue, night sweats, and a rash. Upon admission, he was tachycardic, hypotensive and febrile at 103F. Physical exam revealed a diffuse non-blanching, maculo-papular rash, sparing the face, palms and soles. Labs [...]

Case Presentation: 41-year-old African American female with a history of Systemic lupus erythematosus (SLE) with antiphospholipid syndrome and cocaine abuse presents with acute onset of atypical chest pain, upper respiratory tract infection symptoms, myalgia, and arthralgia with an unremarkable physical examination. The labs were significant for urine drug screen positive for cocaine, elevated troponin, and [...]

Case Presentation: A previously healthy 7-week-old female presented to the infectious disease service with a 7-day history of fever, papular rash of the face and body, edema of the hands and feet, and cracking of the lips. A diagnosis of incomplete Kawasaki Disease (KD) was confirmed by demonstration of aneurysmal dilation of the right coronary [...]

Case Presentation: A 60-year-old previously healthy female presented with a two-week history of intermittent fever with non-pruritic rash, generalized myalgias and arthralgia, weakness, and chest pain. Her exam revealed temperature of 39.3 degrees Celsius, anterior chest tenderness to palpation, diffuse salmon-colored maculopapular rash at bilateral extensor surfaces of upper extremities, and multiple coalescing annular rash [...]

Case Presentation: A 30-year-old female with limited past medical history presented to the emergency department (ED) with 5 days of recurring fevers, nausea, and new rash. The rash was noticeable along her face and arms with pronounced swelling, tenderness, and erythema in her fingers. Initial work-up was significant for hyperferritinemia over 15,000, aspartate aminotransferase of [...]

Case Presentation: A 24 yo male with a history of juvenile idiopathic arthritis ( JIA), macrophage activation syndrome (MAS), and pyoderma gangrenosum presented with fever to 102.9F and rash for 2 days. He had a diffuse, erythematous, un-raised, itchy rash which started on his arms and spread to his chest and back. He had recently [...]

Case Presentation: A 53 yo female presented with a subacute syndrome of intermittent fevers, fatigue, heliotrope rash, weight loss, fingertip necrosis, and nodular skin lesions. Skin biopsy was positive for septal and lobular granulomatous panniculitis. Serology was positive for antinuclear antibody (ANA) and anti-ribonucleoprotein (RNP), negative for other vasculitis and rheumatologic autoantibodies. She was diagnosed [...]

Case Presentation: 24-year-old female presented with greater than one month history of sporadic rash with migratory arthralgias, fevers, and pharyngitis with lymphadenopathy. Patient first developed a sporadic, erythematous, non-pruritic maculopapular rash that would wax and wane during a trip to Mexico two months prior to presentation. Patient also began to experience diffuse migratory arthralgias, starting [...]

Case Presentation: A 21M with a PMHx of juvenile rheumatoid arthritis on chronic prednisone and Ilaris presented with fevers and diarrhea. He was seen by his rheumatologist on morning of presentation for his monthly Ilaris injection, who sent him in when he was found to be hypotensive and febrile in the office. Patient endorsed a [...]

Case Presentation: A 29-year-old female with a past medical history of microcytic anemia and recently-diagnosed AOSD presented with 2 weeks of progressive dyspnea. On her preceding hospital admission, her AOSD was diagnosed and clinical suspicion for MAS was initially mounted. At that time, she demonstrated polyarthralgia, pruritic rash, high-grade fevers, hepatosplenomegaly, diffuse lymphadenopathy, neutrophilic leukocytosis, [...]