Background: Hepcidin-25 is a liver-derived peptide hormone that regulates iron homeostasis in humans. Recent studies have suggested that it also plays a key role in host-pathogen interface. Iron is essential for the survival and growth of bacteria. When the bacteria infect macrophages, macrophages release a number of cytokines, including interleukin-6, which induce hepatic production of [...]

Background: Hepcidin-25 is a liver-derived key peptide hormone that regulates iron homeostasis in humans. Recent studies have suggested that hepcidin also play a key role in host-defense mechanism. Iron is essential for the survival and growth of bacteria. When the bacteria infect macrophages, macrophages release a number of cytokines including interleukin-6, which increase production of [...]

Background: ST-segment elevation myocardial infarction (STEMI) is a cardiac emergency that requires timely reperfusion preferably with cardiac catheterization. The coronavirus disease-2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV2), has adversely impacted the delivery of healthcare to patients with STEMI. Several process changes were observed across the world during this period, including alternative cardiac [...]

Case Presentation: An 85-year-old female presented to the emergency department in August of this year with acute chest pain and shortness of breath. The patient was afebrile, with a heart rate of 97 bpm, a respiratory rate of 24 breaths per minute, and a blood pressure of 191/81 mmHg. Labs showed hemoglobin of 6.6 g/dL [...]