Background: A variety of risk prediction scores have been devised to identify patients at increased risk for VTE in different patient populations and settings. Guideline recommendations for VTE risk assessment vary greatly. We performed a systematic review to identify and synthesize evidence on clinical risk prediction scores for VTE in medical and surgical hospitalized patients. [...]

Background: Venous thromboembolism (VTE) is the leading cause of preventable hospital death. National guidelinesrecommend VTE prophylaxis for all medical patients not at low risk. Several VTE risk prediction models have been developed, but no US models have been validated in a medical population. The ACCP recommends use of the Padua risk assessment model with a [...]

Background: A variety of risk prediction scores have been devised to identify patients at increased risk for VTE in different patient populations and settings. Guideline recommendations for VTE risk assessment vary greatly. We performed a systematic review to identify and synthesize evidence on clinical risk prediction scores for VTE in medical and surgical hospitalized patients. [...]

Background: Venous thromboembolism (VTE) is the leading cause of preventable hospital death. National guidelinesrecommend VTE prophylaxis for all medical patients not at low risk. Several VTE risk prediction models have been developed, but no US models have been validated in a medical population. The ACCP recommends use of the Padua risk assessment model with a [...]

Background: Clinical practice guidelines state that mobility is supposed to play an important role in determining use and duration of pharmacologic VTE prophylaxis. This study examines whether measured mobility levels relate to pharmacologic VTE prophylaxis use among hospitalized older adults. Methods: Prospective observational data from a sample of community-dwelling older adults aged ≥ 60 years, [...]

Background: Guidelines recommend pharmacologic venous thromboembolism (VTE) prophylaxis for high risk hospitalized medical patients that do not have an elevated bleeding risk.  A systematic review of randomized trials estimates the overall bleeding risk with pharmacologic prophylaxis to be low, at 1/1000 (0.1%).  However, it is unclear if the bleeding events were related to pharmacologic prophylaxis [...]

Background: Guidelines and quality performance measures recommend venous thromboembolism (VTE) prophylaxis in patients hospitalized with stroke if they have paralysis or are confined to bed and also recommend that all hospitalized medical patients have VTE risk assessment performed. The Padua Prediction Score is a validated VTE risk prediction model for medical patients based on clinical [...]

Background: Pregnant patients labeled with a penicillin allergy (PcnA) and charted as Group B streptococcus (GBS) positive can spread this infection to their baby during a vaginal delivery resulting in serious illness for their newborns. GBS is the most common cause of infectious morbidity and mortality in the neonatal period during the first week of [...]

Background: Surgical site infections (SSI) can complicate any operative procedure although this risk is mitigated through the use of preoperative antibiotic prophylaxis.  While antibiotic prophylaxis can provide great benefit, inappropriate use can lead to the development of multi-drug resistant organisms causing increased morbidity, mortality, and cost. Although national clinical guidelines for preoperative antibiotics prophylaxis were [...]

Background: Venous thromboembolism (VTE) is a serious and all too frequent hospital complication, therefore assessing each patient’s individual risk of VTE is an important part of their care.  Multiple models are available for risk assessment, however most not only include multiple data points requiring redundant entry, but can be labor intensive and time-consuming to complete on [...]