Background: Semaglutide, a Glucagon-like peptide-1 (GLP-1) agonist, has become one of the most prescribed medications as a result of its beneficial cardiovascular profile and beneficial side effect of weight loss. There is a paucity in literature about its adverse effects. We aimed to conduct a meta-analysis of the severe adverse effects (SAE) of Semaglutide using [...]

Case Presentation: A 70-year-old female with coronary artery disease (s/p drug-eluting stent x 2 10 years ago), Type 2 Diabetes Mellitus, rheumatoid arthritis, Chronic Obstructive Pulmonary Disease, and remote history of bladder cancer presented to the emergency department with two weeks of nausea, jaundice, dark colored urine, loss of appetite, and clay-colored stool. The patient [...]

Case Presentation: A 56-year-old female with past medical history of systemic lupus erythematosus (SLE) on hydroxychloroquine (HCQ) for 30 years, gastroesophageal reflux disease, autoimmune hepatitis on budesonide, asthma, and fibromyalgia presented to the emergency department (ED) with five days of worsening fatigue, bilateral lower extremity weakness, and pain. One week prior, she experienced nausea, heartburn, [...]

Case Presentation: A 74-year-old male with a past medical history of type 2 diabetes presented with weakness, nausea, and weight loss. The patient was on metformin and glipizide at baseline, started on oral semaglutide and uptitrated to a dose of 14 mg one month prior to presentation. He reported a weight loss of 7 kg [...]

Case Presentation: A 58 year old lady with a history of hypertension and gastroesophageal reflux disease, presented to the emergency department with two weeks of jaundice. Vitals were hemodynamically stable, and she was alert and oriented to person, place, and time. Her physical exam was notable for scleral icterus and jaundice. Laboratory values revealed AST [...]