Background: Sepsis is the leading cause of death in US hospitals; prompt recognition and treatment are critical. Early sepsis recognition and treatment varies depending on location (ED/floor/ICU) and evaluation time (presentation vs during stay). “Sepsis response teams” (SRT) improve sepsis care. After our hospital system implemented a “best-practice alert” utilizing Epic’s “sepsis score” (SS) to [...]

Background: Sepsis is a systemic host response to infection that may result in significant morbidity with mortality rates from severe sepsis or septic shock reaching over 20% in most studies.  Research on sepsis has focused on use of groups of sepsis specific interventions (termed care bundles) that are given in response to the declaration of [...]

Background: BACKGROUNDSepsis has been recognized as a major cause of mortality and morbidity in the United States. If not recognized and managed promptly, it can lead to septic shock which is one of the leading causes of deaths in the hospital (WHO, 2020). To promote early identification and treatment of severe sepsis and septic shock, [...]

Background: Obesity is an important risk factor for common chronic conditions, such as diabetes and heart disease. However, obesity has been associated with better outcomes for patients with sepsis. The underlying pathophysiologic basis for this obesity paradox is unclear. We sought to assess patient characteristics, quality of care, and clinical outcomes of patients with obesity [...]