Case Presentation: A 54-year-old woman with type 2 diabetes mellitus with hyperglycemia and hypertension presented to our hospital with new fevers, nausea, vomiting.Four days prior, the patient was found to have a diabetic foot infection and started on trimethoprim/sulfamethoxazole (TMP-SMX) and metronidazole as an outpatient. At this time, her sodium was 133, corrected to 139 [...]

Case Presentation: A 61-year-old man presented to the emergency department with acute onset of fevers, myalgias and generalized erythematous rash after taking five weeks of Trimethoprim-sulfamethoxazole (TMP-SMX) for acute prostatitis. Vital signs were notable for fever and tachycardia, with relative hypotension which responded to initial fluid resuscitation. The patient initially denied abdominal pain however the [...]

Case Presentation: A 41-year-old African American male with a past medical history of overactive bladder and benign prostatic hyperplasia presented to the emergency department (ED) with increasing proximal bilateral lower extremity muscle pain for five days. His pain was accompanied with increasing difficulty with ambulation. The patient also noted persisting hematuria, urgency, and hesitancy for [...]

Case Presentation: A 26-year-old otherwise healthy female was prescribed trimethoprim-sulfamethoxazole (TMP-SMX) for a recurring, spontaneously draining vaginal mass below her urethra with inguinal adenopathy. 5 days after starting TMP-SMX, she developed a full-body rash, fever, myalgia, nausea, and a depressed WBC of 2.4 K/mcL. Possible drug fever was suspected and TMP-SMX was discontinued and covered [...]

Case Presentation: A 31-year-old male with no significant past medical history presented with fever, chills, night sweats, and rash. One week prior, he underwent incision and drainage of a perirectal abscess and was started on a 7-day course of trimethoprim/sulfamethoxazole (TMP-SMX). On the second day following the procedure, he developed fevers, chills, night sweats, and [...]

Case Presentation: A 60-year-old man with a history of alcohol use disorder was admitted to the emergency department due to difficulty moving. The patient was cachectic, agitated, febrile, and tachycardiac. Laboratory results showed hemoglobin 3.2 g/dL, MCV 150.4 fL, WBC 3,300/µL (83% neutrophils, 6.5% lymphocytes), platelets 178,000/µL, LDH 403 U/L, BUN 79.9 mg/dL, creatinine 2.72 [...]