Case Presentation: 66-year-old Caucasian male with history of type 2 diabetes mellitus and prostate cancer presented to the emergency department with 6-week history of progressive weakness. Initially, he noted difficulty arising from a chair signifying weakness in his proximal lower extremity musculature. It then progressed to involve bilateral proximal upper extremities causing difficulty with brushing [...]

Case Presentation: Statin-induced necrotizing autoimmune myopathy (SINAM) is an immune mediated myopathy characterized by proximal muscle weakness and necrosis in the presence of autoantibodies to hydroxyl-methyl-glutaryl-coenzyme-A (HMG-CoA) reductase. It is a rare side effect of statin use that must be recognized quickly in order to prevent the development of irreversible muscle weakness. Most cases occur [...]

Case Presentation: A 51-year-old Caucasian male presented for evaluation of worsening lower extremity muscle weakness and associated myalgias. He received a diagnosis of NAM after three months of progressive proximal, symmetric upper and lower extremity weakness with myalgias, and an initial creatinine kinase (CK) of 13,875 IU/L. He had been on Atorvastatin 40 mg for [...]