Background: As cannabis is legalized/decriminalized in more US jurisdictions, and social norms and perceptions around use change, many products for psychoactive, recreational use, and purported medical uses are available in edible and supplement formats. Rates of unintentional ingestion of cannabis products among children and adolescents have been described in the literature, but there is no [...]

Background: Substance use continues to increase in the United States. Substance use has been linked to new onset cardiovascular and cerebrovascular disorders which lead to hospitalizations. We aimed to assess the association of epidemiology and racial disparities of substance use disorders (SUDs) using the National Inpatient Sample (NIS) Database. Methods: A retrospective study of the [...]

Background: Cannabinoid Hyperemesis Syndrome (CHS) is a rare condition first reported in adolescent patients in 2010. It is associated with episodic abdominal pain, emesis, and intractable nausea which resemble cyclical vomiting syndrome (CVS) in the setting of chronic use of cannabis. (5,12). Evidence of CHS treatment effectiveness in children is limited to case studies and [...]

Background: Readmission among Inflammatory Bowel Disease (IBD) inpatients is common, as is opioid use. Opioid use for IBD has been associated with an increased risk of infection and death, but inconsistently with readmissions. Increasingly, cannabis is viewed as a potentially safer alternative to opioids, though with limited study of potential adverse outcomes such as hospital [...]

Case Presentation: A 60-year-old female with metastatic breast cancer presented with involuntary irregular forceful and painful contractions of facial muscles and dystonic posturing of her hands and feet lasting 5 to 30 minutes. Episodes sporadically occurred up to 20 times daily. MRI brain and spinal cord showed no evidence of metastatic disease or dural enhancement. [...]

Case Presentation: A 79-year-old woman was found minimally responsive in her home and brought to the hospital for evaluation. On arrival, she was bradycardic (32/min) and hypotensive (75/40) without fever, tachypnea (16/min), or oxygen needs (98% room air). Her initial exam was notable for somnolence, conjunctival injection with normal pupils, dry oral mucosa, slightly cool [...]

Case Presentation: A 22 year-old African American male college student presented with acute abdominal pain radiating to the right flank with associated fever, dark urine, and nonbilious nonbloody vomiting. There was no dysuria or change in bowel habits. Medical history was notable for nephrotic syndrome due to biopsy-proven minimal change disease diagnosed at age 17, [...]

Case Presentation: Patient 1:39 week gestation newborn male with a birth weight of 3521 grams. Prenatal course was overall uncomplicated. Mother was a 27 year old G2P2 woman who had used medical cannabis several times a week during pregnancy for PTSD, anxiety and headaches. No other non-prescribed substances were used and umbilical cord toxicology testing [...]

Case Presentation: A 42 year-old male patient with past medical history of asthma presented to the emergency room with acute onset epigastric pain for three days. The epigastric pain worsened over time, and the patient subsequently experienced numerous episodes of vomiting and the inability to tolerate oral intake, including both solids and liquids. He described [...]

Background: Unintentional ingestion of cannabis products among children and adolescents is well described, but we found no summary of presentations among adults. Methods: We performed a scoping literature review of presenting symptoms, sources of exposure, and clinical courses of adults who seek medical care following unintentional ingestion of psychoactive cannabis or intentional ingestion of cannabidiol [...]