Background: Approximately 10% adults with Sickle Cell disease (SCD) has Pulmonary hypertension (PHTN). There are several etiologies like hypoxia driven and microvascular obstruction contributing to PHTN. However, the in-hospital outcomes of PHTN on SCD has not been well studied. Methods: We queried 2018 National Inpatient Sample (NIS) database to identify SCD and different types of [...]

Case Presentation: A five-year-old boy with autism presented to the hospital with two-months of fatigue, lower extremity pain, and a petechial rash. Review of systems was notable for a two-kilogram weight loss, intermittent gingival bleeding and refusal to walk for one week. On admission he was afebrile with a heart rate of 160 beats per [...]

Case Presentation: A 48-year-old female with no known medical history presented after a syncopal episode and one week of malaise and fatigue. She was diagnosed with high output heart failure complicating severe pulmonary hypertension. Hemoglobin was 2.7 g/dL with MCV of 50 fL. She denied menorrhagia, melena, hematuria or hematemesis as well as weight loss [...]

Case Presentation: A 56-year-old male with WHO Group I/III pulmonary hypertension (PH), Gold Stage III COPD, and right ventricular failure presented with several weeks of gradually worsening dyspnea. One month prior, he was hospitalized for an acute exacerbation of PH and was discharged on an increased dose of ambrisentan after excluding intra-atrial shunting. On the [...]

Case Presentation: A 74-year-old female with a past medical history of chronic pulmonary emboli, left ventricular heart failure, and hypertension presented with shortness of breath on exertion and bilateral lower extremity edema for one week. On examination, she was found to have jugular venous distention, crackles in bilateral lung bases, and 3+ pitting peripheral edema. [...]

Case Presentation: We report here a case of high output heart failure (HOHF), a rare but potential complication of Arteriovenous fistula (AVF) in a post-renal transplant patient.A 60-year-old male with end-stage renal disease and subsequent renal transplant 3 months ago presented with exertional dyspnea, worsening anasarca, and weight gain of 20 pounds. The patient also [...]

Case Presentation: Pulmonary hypertension (PH) affects 1% of the global population, including 10% of people over 65 and ~50% of people with Congestive Heart Failure (CHF). Pulmonary hypertension (PH) is classified into 5 clinical subgroups: pulmonary arterial hypertension (PAH), PH due to left-sided heart disease, PH due to chronic lung disease, PH due to chronic [...]

Case Presentation: A 45-year-old woman with a history of ER-/PR-/Her2+ breast cancer previously in remission, recently diagnosed with recurrent metastatic breast cancer pathologically and on imaging, presented to the hospital with multiple days of dyspnea and dry cough. Vitals were remarkable for hypoxia and tachycardia. Electrocardiogram showed sinus tachycardia without ischemic changes. Troponin and B-type [...]

Case Presentation: A 68-year-old previously healthy woman was presented to our hospital with acute low back pain that was not triggered by any trauma. Magnetic resonance imaging (MRI) revealed a lumbar compression fracture, and she was admitted to the orthopedic department. Two days later, she developed orthopnea and hypotension, and therefore the orthopedician consulted with [...]

Case Presentation: A 64 year-old male with a history of childhood polio leading to severe kyphoscoliosis presented to our hospital with four months of progressively worsening shortness of breath and was found to be in acute hypoxic and hypercapneic respiratory failure requiring noninvasive positive pressure ventilation (NPPV). On exam, he was altered and not responding [...]