Background: Antibiotics targeted against C. difficile bacteria are necessary, but insufficient, to achieve a durable clinical response because they have no effect on C. difficile spores that germinate within a disrupted microbiome. ECOSPOR-III evaluated SER-109, an investigational, biologically-derived microbiome therapeutic of purified Firmicute spores for treatment of recurrent CDI. Methods: Adults ≥18 years with recurrent […]

Background: Survivors of hospitalization for COVID-19 are potentially at high risk for subsequent psychiatric morbidity due to medical trauma, systemic inflammation, and potential neurotropism of SARS-CoV-2(1). In addition, social isolation during the hospital stay due to restrictive visitor policies and after discharge due to fears of contagion or stay-at-home orders could further increase psychiatric vulnerability […]

Background: Despite evidence that the use of medications for patients with opioid use disorder (OUD) leads to reduced mortality and improved engagement in outpatient addiction treatment, these life-saving medications are underutilized in the hospital setting. This study reports the outcomes of a hospitalist-led interprofessional and multidisciplinary inpatient program, known as the B-Team (buprenorphine team), to […]

Background: A small number of patients account for a disproportionate number of hospital readmissions. The Complex High Admission Management Program (CHAMP) is designed to improve care and reduce hospitalizations for frequently readmitted patients. Non-randomized studies of CHAMP found reductions in readmission but may be subject to regression to the mean. We conducted a randomized trial […]

Background: The COVID-19 pandemic has necessitated rapid changes in healthcare delivery in the United States, including changes in the care of hospitalized children. Our study aimed to identify the major changes in inpatient pediatric healthcare delivery and potential learnings from these changes. Methods: We conducted semi-structured interviews for this qualitative study. We purposefully sampled hospitals […]

Background: Procedural complications are a common source of adverse events in hospitalized patients(1, 2). In academic centers, bedside procedures have traditionally been performed by trainees, often without experienced proceduralist supervision, or referred to interventional radiology or consultant services, often with an associated delay in procedure performance. Many trainees report discomfort with their skill in performing […]

Background: The Choosing Wisely Campaign started in 2012 with the aim of promoting high-value care. On its Choosing Wisely List, the Society of Hospital Medicine cited daily basic metabolic panel (BMP) and complete blood count (CBC) testing in the absence of clinical suspicion as unnecessary practice. Since the implementation of Choosing Wisely, there have been […]

Background: As a result of COVID-19, clinical care across the U.S. has changed with virtual services becoming the new normal in many clinics.1-5 How these changes impact patient care following hospitalization is unclear as data are limited.6 We report on characteristics and rates of clinic follow up and satisfaction with care in patients discharged during […]

Background: Literature on the prognostic value of laboratory tests on patients hospitalized with COVID-19 is sparse.1-4 Based on available evidence our institution developed a protocol for care of patients admitted with COVID-19. In addition to routine labs (complete blood count, complete metabolic panel, venous lactate, etc.), the protocol recommends a set of COVID-specific daily lab […]

Background: In 2013, the American Academy of Pediatrics’ position statement, “Guiding Principles for Pediatric Hospital Medicine (PHM) Programs,” emphasized the importance of professional development for each PHM physician. However, little is published about PHM physicians’ perspectives on professional development. The objectives of this study were to explore pediatric hospitalists’ perceptions of professional development needs, desired […]