Background: Vitamin K antagonists (VKA) remain widely used in the treatment of venous thromboembolism (VTE). During surgical interventions, the prevention of recurrent VTE must be weighed against the increased bleeding risk conferred by anticoagulation. There is a lack of strong evidence to guide the optimal periprocedural management of anticoagulation in patients with prior VTE, and [...]

Background: Venous thromboembolism (VTE) in hospitalized medically ill patients is a leading preventable cause of morbidity and mortality in the United States. About half of VTE events occur following discontinuation of standard-duration in-hospital prophylaxis and hospital discharge. The APEX study evaluated Betrixaban for in-hospital to home VTE prophylaxis and is the first FDA approved anticoagulant [...]

Background: Venous thromboembolism (VTE) in hospitalized medically ill patients is a leading preventable cause of morbidity and mortality in the United States. About half of VTE events occur following discontinuation of standard-duration in-hospital prophylaxis and hospital discharge. The APEX study evaluated Betrixaban for in-hospital to home VTE prophylaxis and is the first FDA approved anticoagulant [...]

Background: Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a serious public health problem causing over 90,000 deaths each year. VTE rates at our institution have been high and costly, with insurer penalties for post-operative VTE exceeding $5.5M in 2014. While prophylaxis for at-risk inpatients can reduce hospital-associated (HA) VTE by up [...]

Background: Mobile health applications have the potential to support patients via improved engagement and self-management. While the use of this technology has been developed for patients with chronic diseases, there is limited evidence to guide the development of this technology for patients with acute conditions. Patients diagnosed with acute venous thromboembolic disease (VTE) are at [...]

Case Presentation: A 68-year-old man presented to the Emergency Department complaining of diaphoresis with concomitant alerts on his Apple Watch which reported his heart rate was irregular. He has a known history of CAD with previous stent placement but did not report any chest pain, shortness of breath, palpitations, or recent medication changes. He did [...]

Case Presentation: A 60-year-old male patient who presented with hemoptysis 1-year prior, was found to have sub-centimeter lung nodules and multiple liver lesions on CT chest. The largest hepatic lesion on abdominal MRI was 3.2 x 1.4cm. He declined liver biopsy and presented a year later with abdominal distension, early satiety and unintentional weight loss [...]

Case Presentation: A 64-year-old year old woman with no personal or family history of HTN was diagnosed with right renal angiomyolipoma incidentally on work up for latent TB and referred to interventional radiology for partial right RAE. On routine follow up one week post procedure, she was noted to be normotensive. One-month post procedure while [...]

Case Presentation: A 52 year-old man was hospitalized for hypoxia one month after surgery for ruptured appendicitis. He also reported abdominal pain and steatorrhea along with a 50 pound weight loss in five months. On exam he was anicteric but cachectic. CT pulmonary angiogram on admission revealed peripheral-based pulmonary lesions concerning for septic emboli and [...]

Case Presentation: A 34-year-old Caucasian lady with metabolic syndrome and hypertension presented with a sudden onset 10/10 right lower extremity pain associated with numbness and inability to ambulate. Vital signs were stable. On examination, her right lower extremity was pale, cold and pulseless. Her laboratory tests including hypercoagulable workup were normal. A CT aortogram with [...]