Background: Patients hospitalized with COVID-19 can clinically deteriorate in the second week of illness after a period of initial stability. Thus, an important clinical question is determining when it is safe to discharge these patients from the hospital without overwhelming hospitals’ capacities. Unfortunately, discharge criteria for COVID-19 patients are often based on expert opinion, with [...]

Background: Survivors of hospitalization for COVID-19 are potentially at high risk for subsequent psychiatric morbidity due to medical trauma, systemic inflammation, and potential neurotropism of SARS-CoV-2(1). In addition, social isolation during the hospital stay due to restrictive visitor policies and after discharge due to fears of contagion or stay-at-home orders could further increase psychiatric vulnerability [...]

Background: Hospitalizations to treat SARS-CoV-2 infected patients have strained health systems worldwide. Monitored outpatient management of select low-risk COVID-19 patients with isolated exertional hypoxia could help preserve hospital resources and reduce costs while aiming to maintain a high standard of care. In this retrospective cohort analysis, we aimed to evaluate the safety and effectiveness of [...]

Background: Early risk stratification scores utilizing data available at the bedside have been used regularly to identify patients at greatest risk of poor outcomes from rapidly evolving conditions like sepsis. Little is known about how point-of-care scores developed for sepsis perform at predicting outcomes in large, heterogeneous cohorts of patients with COVID-19. Our objective was [...]

Background: Glucagon-like peptide-1 (GLP-1) agonists are increasingly prescribed for obesity and type 2 diabetes, demonstrating efficacy in weight loss and glycemic control [1-3]. Beyond metabolic effects, these medications show protective effects against renal disease progression and reduce major adverse cardiovascular events [4]. GLP-1 agonists influence body composition through effects on both fat mass and fat-free [...]

Background: The COVID-19 pandemic has necessitated rapid changes in healthcare delivery in the United States, including changes in the care of hospitalized children. Our study aimed to identify the major changes in inpatient pediatric healthcare delivery and potential learnings from these changes. Methods: We conducted semi-structured interviews for this qualitative study. We purposefully sampled hospitals [...]

Background: As a result of COVID-19, clinical care across the U.S. has changed with virtual services becoming the new normal in many clinics.1-5 How these changes impact patient care following hospitalization is unclear as data are limited.6 We report on characteristics and rates of clinic follow up and satisfaction with care in patients discharged during [...]

Background: Literature on the prognostic value of laboratory tests on patients hospitalized with COVID-19 is sparse.1-4 Based on available evidence our institution developed a protocol for care of patients admitted with COVID-19. In addition to routine labs (complete blood count, complete metabolic panel, venous lactate, etc.), the protocol recommends a set of COVID-specific daily lab [...]

Case Presentation: We report the case of a 69-year-old Honduran male with a long history of non-valvular atrial fibrillation with a CHA2DS2-VASc Score= 2 (Age > 65 and Hypertension) anticoagulated with Rivaroxaban 20 mg po daily since 2013.  He presented with sudden onset of excruciating upper and lower back pain while seated at his cardiologist’s [...]

Case Presentation: A 44-year-old female with end-stage renal disease on hemodialysis presented to the hospital with progressive nausea, vomiting and abdominal pain. The etiology of her renal disease was unknown. She had received a renal transplant 17 years ago, which then failed. She was maintained on peritoneal dialysis (PD) for 12 years until she was [...]