Background: Among patients undergoing cardiac surgery on cardiopulmonary bypass (CPB), post-operative complications are common, occurring in up to 67% of patients, and significantly impact long-term outcomes. We conducted a Phase 2 clinical trial of RBT-1, a pharmacologic preconditioning drug, to assess cytoprotective biomarkers and clinical outcomes. Herein, we report our final results. Methods: This randomized, [...]

Case Presentation: A 27-year-old woman with history of hypertension, diabetes mellitus, hyperlipidemia, and family history of sudden cardiac death presents to the hospital with complaints of substernal chest pain and palpitations. She has a history of recurrent chest pain following multiple COVID-19 infections. Labs were unremarkable except uncontrolled glucose level. Electrocardiogram demonstrated normal sinus rhythm. [...]

Case Presentation: A 64 year old female with a past medical history of coronary artery disease and coronary artery bypass graft, heart failure with reduced ejection fraction, diabetes mellitus, peripheral arterial disease, hyperlipidemia and a strong smoking history presented to the emergency department with exertional dyspnea worsening over the past 1 month and substernal chest [...]