Case Presentation: Hemophagocytic lymphohystiocytosis (HLH) is a rare cause of pancytopenia. Patients with sickle cell disease can present with pancytopenia and recognition of (HLH) in patients with sickle cell disease may be a lifesaving diagnosis.Case presentation:A 39-year-old female with past medical history of sickle cell anemia and moyamoya disease was admitted with sickle cell vaso-occlusive [...]

Case Presentation: A 35 year old female with no significant past medical history developed fever late in the third trimester of her second pregnancy. The prior and current pregnancy had been uneventful.  The fever was believed to be viral and she rested at home.  After being seen by her OB with persistent fever, she was [...]

Case Presentation: A 29-year-old Caucasian woman presented to the emergency department with fever, sore throat, epigastric and right upper quadrant abdominal pain of 5 days duration. Physical examination was positive for fever (40oC), tachycardia (heart rate 114 beats per minute), and a palpable liver and spleen on abdominal examination. Notable laboratory investigations included pancytopenia – [...]

Case Presentation: A 31-year-old male with a past medical history significant for treated syphilis presented with a three-month history of recurrent fevers. Despite close outpatient follow-up and extensive workup, his symptoms persisted prompting him to go to the ED.On presentation, the patient was febrile, hypotensive, and tachycardic. He was admitted for sepsis and was started [...]

Case Presentation: A 26-year-old man with history of virally undetectable HIV, presented with 3 weeks of intermittent fevers and night sweats associated with chills, non-productive cough and generalized weakness, but denied weight loss. Vital signs revealed fever of 101.3F, tachycardia (pulse 118 bpm) and hypotension (blood pressure 95/61 mmHg). Physical exam revealed cervical and axillary [...]

Case Presentation: A 60-year-old previously healthy female presented with a two-week history of intermittent fever with non-pruritic rash, generalized myalgias and arthralgia, weakness, and chest pain. Her exam revealed temperature of 39.3 degrees Celsius, anterior chest tenderness to palpation, diffuse salmon-colored maculopapular rash at bilateral extensor surfaces of upper extremities, and multiple coalescing annular rash [...]

Case Presentation: A 70-year old-man with a history of HLA-B27-associated anterior uveitis, spondyloarthropathy, and drug- induced leukocytoclastic vasculitis on chronic prednisone and mycophenolate, presented with 3-weeks of worsening fatigue and weakness. At admission, he was afebrile, tachycardic, and had a diffuse rash. On day 2, he began spiking fevers. Labs were notable for WBC count [...]

Case Presentation: A 23-year-old male with granulomatosis with polyangiitis with renal involvement (on azathioprine), stage 4 chronic kidney disease (baseline renal function) presented with fever, weight loss, and new pancytopenia. Broad-spectrum antibiotics were started and a comprehensive infectious work-up was done, including bacterial cultures, viral tests, and fungal serologies. Initial imaging was unremarkable for any [...]

Case Presentation: A 57-year-old man with congestive heart failure and coronary artery disease presented with shortness of breath of two days duration. He denied fevers, chills, chest pain, or cough. Presenting vitals were significant for oxygen saturation of 80%, requiring. All other vitals were within normal limits. Physical exam was unremarkable. His labs were significant [...]

Case Presentation: A 34 year-old female with a history of anxiety and depression initially presented to an outside hospital and then was transferred to our facility for jaundice. She had given birth 2 months prior to presentation to a healthy child; however, the pregnancy was complicated by severe preeclampsia. On exam, she had a high-normal [...]