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Abstract Number: 38
SHM Converge 2021
Background: For 6 months in 2018, a major quaternary-care teaching hospital underwent closure of operating rooms (OR) and cardiac catheterization laboratory (CCL) due to flooding/sterilization issues and planned upgrades. Surgery and interventional cardiology trainees were reassigned to other teaching hospital sites of Yale School of Medicine, with the anticipated impact on Medicine/subspecialties not fully known. […]
Abstract Number: 49
Hospital Medicine 2020, Virtual Competition
Background: When left untreated tuberculosis has the potential to cause significant morbidity and mortality. In many instances adequate microbiologic therapy does not exclude chronic respiratory complications. Bronchostenosis is an under recognized complication with potentially far reaching complications. Methods: Patients with evidence of bronchial stenosis and lung volume loss who were previously treated with pulmonary tuberculosis […]
Abstract Number: A7
SHM Converge 2022
Background: Microbiota-based treatments have shown promise to reduce recurrence for recurrent Clostridioides difficile infections (rCDI), but consistent and reliable safety data are needed to support regulatory approvals and broaden patient access. Here we provide cumulative safety data from 5 prospective clinical studies evaluating RBX2660—a standardized, microbiota-based investigational live biotherapeutic—for reducing rCDI. Methods: This analysis included […]
Abstract Number: E6
SHM Converge 2022
Background: Recurrent Clostridioides difficile infection (rCDI) is an urgent public health threat. RBX2660 is a standardized, stabilized, investigational microbiota-based live biotherapeutic that has been evaluated in 5 prospective clinical trials. Eligibility criteria in clinical trials are often narrowly defined, excluding broader patient populations. Herein, we report a retrospective analysis of safety and efficacy of RBX2660 […]
Abstract Number: 114
Hospital Medicine 2016, March 6-9, San Diego, Calif.
Background: Obesity affects a large majority of the U.S. population, and hospitalizations may represent opportunities to intervene and promote weight loss. We sought to determine if multidisciplinary patient-centered inpatient weight loss consults, post-discharge telephone text messages, and primary care follow up could result in weight loss. Methods: We conducted a feasibility study comparing 25 obese […]
Abstract Number: 124
SHM Converge 2023
Background: Axial spondyloarthritis (axSpA) takes two forms – radiographic (also known as ankylosing spondylitis(AS)) and non-radiographic (nr-axSpA). The symptoms caused are similar with chronic back pain, but nr-axSpA damage cannot be seen on X-rays. Historically, nonradiographic axial spondyloarthritis (nr-axSpA) did not have any approved codes so clinicians had to use AS and other codes. Starting […]
Abstract Number: 125
SHM Converge 2023
Background: Antibiotics used to treat Clostridioides difficile infection (CDI) can predispose patients to recurrent CDI (rCDI). Gut microbiome restoration by fecal microbiota transplantation is recommended by multiple guidelines after ≥2 episodes of rCDI, with no guideline-recommended options to restore the microbiome earlier in the course of CDI. RBX2660 is a standardized, microbiota-based live biotherapeutic being […]
Abstract Number: 127
SHM Converge 2023
Background: Clostridioides difficile is an opportunistic pathogen that causes an estimated 500,000 infections per year in the United States. RBX2660, a standardized, microbiota-based live biotherapeutic, is being investigated as a treatment option for recurrent C. difficile infection (rCDI). RBX2660 has demonstrated consistent tolerability and efficacy in reducing rCDI across 6 clinical studies. We present a […]
Abstract Number: 128
Hospital Medicine 2016, March 6-9, San Diego, Calif.
Background: Functional decline during hospitalization of older adults is well-recognized and potentially preventable. Recent studies have suggested that clinically significant functional decline also affects hospitalized adults under 65 years of age, and that physical function is an important predictor of hospital readmissions. Despite the importance of function, we lack simple, efficient, and standardized measures to […]
Abstract Number: 130
SHM Converge 2023
Background: Patients spend about 95% of their hospitalization in bed, increasing the risk of functional decline associated with adverse events and readmissions. Some hospitals track patients’ functional mobility trends using Activity Measure for Post-Acute Care 6-Clicks Inpatient Short Form (AM-PAC). We aim to understand the associations between functional mobility loss from hospital admission to discharge, […]