Background: Previous research has established that treating COVID-19 hospitalized patients with remdesivir (RDV) was associated with significantly lower hospital readmission rates. We extend prior research with an additional year of more recent data by examining the association between RDV use and 30-day readmission rates due to any cause as well as due to COVID-19 among [...]

Background: We observed improved survival among COVID-19 patients receiving remdesivir (RDV) during the early parts of the pandemic (Aug-Nov 2020) [1]. Clinical management of COVID-19 continues to develop over time as variants of concern (VOC) evolve. We extend the previous study to characterize outcomes for patients admitted on low-flow oxygen (LFO) and compare hospital all-cause [...]

Background: Contemporary treatment for COVID-19 includes the use of SARS-2-CoV direct-acting antivirals (DAAs). An FDA assessment in the Medicare and Veterans Affairs population has suggested that individual agents in this class have significant differences in drug-drug interaction (DDI) potential based on their pharmacokinetic profiles; however, the clinical impact is not well established. We sought to [...]

Case Presentation: This is a 50-year-old woman with a history of Rheumatoid Arthritis on Rituxan and methylprednisolone, COVID-19, MGUS, and recent admissions for bacterial pneumonia and fever of unknown origin who presented with fevers, rigors, and dizziness. Of note, she had tested positive for COVID-19 on 4/2020 via a nasopharyngeal swab, and states fevers began [...]

Case Presentation: A 28 year old pregnant female G1P0 (31 weeks) presented with shortness of breath and fever. She was Covid-19 positive by PCR. We present a case of a pregnant woman with Covid-19. On admission she was hypoxic with oxygen saturation of 94% on 6 liters oxygen. Pulse 120-130, Temp 101 F. PE was [...]

Case Presentation: A 50-year-old female with rheumatoid arthritis who received 6-monthly maintenance Rituxan infusions, developed COVID-19 and was hospitalized with acute hypoxic respiratory failure. She was treated with 5 days of Remdesivir and discharged with 3L supplemental oxygen to complete a 10-day course of Dexamethasone. She didn’t improve to baseline and was re-hospitalized with progressively [...]

Background: Constraints on resources require healthcare systems to implement alternative and innovative means for delivering care. The COVID-19 pandemic amplified this issue throughout the world, leading to shortages of ventilators, hospital beds, and healthcare personnel. We report the results of an Acute Care at Home (ACH) program’s response to COVID-19, providing in-home hospital-level care to [...]

Background: More frequently, clinicians encounter patients with mild-to-moderate COVID-19 (defined as patients whose oxygen saturation remains above 94% on room air)1 in the hospital setting.2 These patients may have acquired COVID-19 in the hospital or have tested positive for COVID-19 while presenting to the hospital for another condition.3 Many of these patients are high risk [...]