Background: Among patients undergoing cardiac surgery on cardiopulmonary bypass (CPB), post-operative complications are common, occurring in up to 67% of patients, and significantly impact long-term outcomes. We conducted a Phase 2 clinical trial of RBT-1, a pharmacologic preconditioning drug, to assess cytoprotective biomarkers and clinical outcomes. Herein, we report our final results. Methods: This randomized, [...]

Case Presentation: A 27-year-old woman with history of hypertension, diabetes mellitus, hyperlipidemia, and family history of sudden cardiac death presents to the hospital with complaints of substernal chest pain and palpitations. She has a history of recurrent chest pain following multiple COVID-19 infections. Labs were unremarkable except uncontrolled glucose level. Electrocardiogram demonstrated normal sinus rhythm. [...]

Case Presentation: We present the case of a 64-year-old male with a history of pulmonary embolism status post IVC filter, and recent viral constrictive pericarditis with exudative pericardial effusion requiring pericardiocentesis and bilateral pleural effusions requiring chest tubes, who was admitted for dyspnea, cyanosis, and confusion. Vitals were blood pressure 78/51, heart rate 60, respiratory [...]

Case Presentation: A 64 year old female with a past medical history of coronary artery disease and coronary artery bypass graft, heart failure with reduced ejection fraction, diabetes mellitus, peripheral arterial disease, hyperlipidemia and a strong smoking history presented to the emergency department with exertional dyspnea worsening over the past 1 month and substernal chest [...]