Case Presentation: A 53-year-old gentleman with metastatic adrenocortical carcinoma with liver and lung metastases, was recently started on pazopanib, a non-specific tyrosine kinase inhibitor. He was brought to the hospital by family for increasing confusion and decreased oral intake. He was hemodynamically stable and afebrile on presentation. Initial labs were significant for low platelet count [...]

Case Presentation: Atypical (complement-mediated) Hemolytic-Uremic Syndrome is a rare but life threatening thrombotic microangiopathy that affects patients of all ages. About 33-40% of patients sustain end-stage renal disease, stroke, myocardial infarction or have mortality during the first presentation of this syndrome. We present a case of a 32-year-old previously healthy male who presented to the [...]

Case Presentation: A 20 year old woman with a history of astrocytoma of thoracic and lumbar spine status post resection with subsequent neurogenic bladder and bowel presented with acute encephalopathy following a viral illness. Initial workup showed acute kidney injury (creatinine 2.21 mg/dL), normal hemoglobin (12 g/dL), new thrombocytopenia (platelet 60 K/uL), and urinalysis suggestive [...]