Case Presentation: A 48-year-old female with AIDS, HFrEF, asthma, and hypertension presented with weight loss, fatigue, chills, abdominal pain, vomiting, left neck swelling, and purulent mouth drainage over the last 2-3 weeks. She was febrile to 102.9 F, hypotensive (85/64), tachycardic, tachypneic, and had firm, mobile, 2-3 cm cervical lymph nodes and enlarged tonsils. Labs [...]

Case Presentation: IntroductionHistoplasmosis is a fungal infection caused by histoplasma capsulatum, a dimorphic fungus endemic in central and eastern United States. Even in immunocompromised patients, the reported incidence of CNS manifestations in disseminated histoplasmosis is only about 5-10%. This report presents an unusual case of recurrent histoplasma meningitis in a patient with prior history of [...]

Case Presentation: A 40-year-old man with inconsistently treated HIV infection presented with a progressive cough, dyspnea, and pleuritic chest pain over a two-week period which were associated with fevers, chills, night sweats, and a 40-pound weight loss. He emigrated from Mexico 10 years prior and had traveled to the central valley of California. On physical [...]

Case Presentation: A 54-year-old male with known human immunodeficiency virus (HIV) presented to the emergency room with three weeks of progressive lower abdominal pain, nausea, chills, and a 15-lb weight loss. The patient had no diarrhea, dysuria, urinary frequency, or penile discharge. He had no recent sexual activity. He was diagnosed with HIV four years [...]

Case Presentation: A 48-year-old man with end-stage renal disease due to IgA nephropathy underwent a deceased donor kidney transplant in 2008, which resulted in graft failure. A second transplant in 2019 required additional thymoglobulin due to high panel reactive antibodies and was complicated by BK nephritis, treated with leflunomide. Since treatment, he had persistent leukopenia, [...]

Case Presentation: A 33-year-old female with a renal transplant 18 months prior was transferred to our hospital with acute kidney injury after presenting with acute gastrointestinal symptoms. One year earlier, a biopsy of the transplanted kidney revealed budding yeast consistent with Histoplasma capsulatum. Histoplasma urine and serum antigens were negative, and Itraconazole was discontinued after [...]