Background: The ratio of partial pressure of arterial oxygen to the fraction of inspired oxygen (P:F ratio) has known clinical utility. For example, it is a key component of the sequential organ failure assesment (SOFA) score which is a validated mortality predictor and the new operational defintion of sepsis. Yet, its use is limited because [...]

Background: We observed improved survival among COVID-19 patients receiving remdesivir (RDV) during the early parts of the pandemic (Aug-Nov 2020) [1]. Clinical management of COVID-19 continues to develop over time as variants of concern (VOC) evolve. We extend the previous study to characterize outcomes for patients admitted on low-flow oxygen (LFO) and compare hospital all-cause [...]

Case Presentation: A 14yo girl presented with syncope and 4 days of URI symptoms. She had no past medical or family history. On presentation, she was hypotensive with mildly elevated lactate, troponin, and BNP, and an unremarkable ECG and chest radiograph. Initial echocardiogram showed normal LV function. Cardiac MRI revealed a pericardial effusion and increased [...]

Background: All oxygenation devices are the aerosol-generating procedures and can generate some contaminated aerosols and droplets from the patient’s airway and transmit them through the air, especially in close contact or in an enclosed space. Increasing the flow rate in O2 devices can provide more FiO2, such as using HFNC, which can improve the hypoxia [...]