Case Presentation: Hemophagocytic lymphohystiocytosis (HLH) is a rare cause of pancytopenia. Patients with sickle cell disease can present with pancytopenia and recognition of (HLH) in patients with sickle cell disease may be a lifesaving diagnosis.Case presentation:A 39-year-old female with past medical history of sickle cell anemia and moyamoya disease was admitted with sickle cell vaso-occlusive [...]

Case Presentation: A 72-year-old man with a history of Crohn’s disease and hypertension presented to the emergency department with one month of worsening fatigue, anorexia with weight loss and headaches. The patient also noted intermittent high-grade fever up to 105 degrees Fahrenheit of one week’s duration.One month before presentation, the patient had returned to NYC [...]

Case Presentation: A 65-year-old woman with hepatitis C-induced liver cirrhosis status-post liver transplantation, coronary artery disease and gout, presents with one week of progressive fatigue, weakness, and severe pain in her right leg and left shoulder. She was on atorvastatin for cardiac disease and had recently started Ledipasvir/Sofosbuvir for hepatitis C two months prior. She [...]

Case Presentation: 37 year-old male with a medical history significant for intravenous drug usage presented with three years of progressive generalized symptoms including weight loss, fevers, and shortness of breath. The patient started to experience worsening fatigue, drenching night sweats and an unintentional weight loss exceeding 20 pounds over several months leading to admission. Upon [...]

Case Presentation: A 29 year-old Hispanic male with past medical history of AIDS and multiple-associated co-infections including CNS toxoplasmosis, CMV retinitis, genital HSV, PCP, noncompliance and multiple substance abuse, presented to the ED with 10 days of watery non-bloody diarrhea, abdominal pain, fever, chills, anorexia and dry cough. Patient was admitted for similar symptoms nine [...]

Case Presentation: A 45 year old female with history of psoriatic arthritis and renal transplant from a living unrelated donor (performed in the Philippines in 2014) presented with symptoms of fever, fatigue, weakness, tremors, epigastric pain, and loose stools. At the time of presentation, she had recently completed three cycles of plasmapharesis/IVIG and one cycle [...]

Case Presentation: A 75 year old woman with past medical history of hypothyroidism presented with weakness and the sensation of “large folds of skin” on the bottom of her feet. Pertinent physical exam findings included conjunctival pallor, nonspecific diffuse abdominal tenderness, and hyperpigmented macules of the dorsal finger tips and soles, which were also new [...]

Case Presentation: A 55-year-old man with a history of chronic alcohol abuse, anxiety, and Crohn’s disease treated with right hemicolectomy and ileocolic anastomosis 30 years ago presented with symptoms of altered mental status, generalized weakness, and weight loss for 10 days. He endorsed chronic diarrhea but was not on immunosuppressants. He had a temperature of [...]

Case Presentation: An 18-year-old male with no significant past medical history presented with four days of worsening fever, sore throat, nausea, vomiting, headache, and difficulty swallowing. One month prior, he presented to an urgent care with an enlarged tender lump below his chin and swollen lymph nodes. He was diagnosed with infectious mononucleosis (IM) and [...]

Case Presentation: A 76-year-old white woman with a past medical history of RA, being treated with MTX, sarilumab, and folic acid supplementation, presented to the hospital for worsening pain and lethargy. Physical exam displayed dry mucous membranes, ulcerations throughout the oropharynx, and purple digits from distal interphalangeal joints to the fingernails bilaterally. Additionally, she was [...]