Background: Approximately 5-10% of the US population reports a Penicillin (PCN) allergy. Only 1 in 10 of these patients are found to have a positive reaction to PCN. This label comes at a grave cost, with higher incidences of multidrug-resistant nosocomial infections reported among these patients. With the lack of novel antibiotics and the alarming [...]

Background: Approximately 5-10% of the US population reports a Penicillin (PCN) allergy. Only 1 in 10 of these patients are found to have a positive reaction to PCN. This label comes at a grave cost, with higher incidences of multidrug-resistant nosocomial infections reported among these patients. With the lack of novel antibiotics and the alarming [...]

Background: Skin, soft tissue, and joint infections are common in pediatric patients and can require invasive procedures to drain purulent fluid. Atypical pathogens (fungal and acid-fast bacilli [AFB]) are important but rare causes of these infections with reported case rates as low as 0.6-1.6 cases/100,000 a year. Despite the rarity of these infections, costly atypical [...]

Background: Despite detailed Infectious Disease Society of America (IDSA) skin and soft tissue infection guidelines, patients with cellulitis at our institution consistently receive antibiotics with high local resistance or that are inappropriate based on IDSA guidelines. Our baseline data showed that 55 percent of patients receive antibiotics per IDSA guidelines and only 33 percent of [...]

Background: The management of cellulitis in young infants has not been well-studied and appears to be largely variable. Infants with cellulitis often present without fever and only skin findings, with only a small minority having invasive infection. There is no consensus on the need for admission and further workup, such as a lumbar puncture. The [...]

Case Presentation: Immunotherapy is an emerging therapeutic option in the field of oncology. Dermatological toxicities are the most prevalent immune-related adverse events associated with immunotherapy. Herein, we report a case of a 60-year-old male who developed localized bullous pemphigoid after nearly a year of treatment with a PD-1 inhibitor, nivolumab, for metastatic renal cell carcinoma. [...]

Case Presentation: A 68-year-old man presented with dyspnea, wheezing and productive cough. He was hypoxemic and a chest radiograph revealed a left lower lobe infiltrate and he was admitted with a Chronic Obstructive Pulmonary Disease exacerbation and pneumonia. His troponin was mildly elevated and he was started on a heparin infusion. The intravenous line infusing [...]

Case Presentation:      A 30  year old African American  female with history of Systemic Lupus Erythematosus  and secondary Lupus nephritis presented with painful erythematous blisters on her hands and feet along with dysphagia and oral ulcers.  It was  discovered that 2 weeks  prior she was started on mycophenolate mofetil for treatment of her lupus [...]

Case Presentation: A 22-year-old male with a history of atopic dermatitis presented with worsening of eczema lesions around his eyes and mouth with blurring of vision bilaterally despite being on oral antibiotics. 2 weeks ago he was treated with a steroid taper for eczema flare in his forearms. Patient reported that he has always had eczema patches around his [...]

Case Presentation: A 68-year-old white male with a history of Factor V Leiden, deep vein thromboses (DVT), pulmonary embolism (PE), atrial fibrillation, and hyperthyroidism on warfarin therapy for 12 years presented to the emergency department (ED) with acutely worsening, bilateral, black, necrotic ulcerations of his lower extremities with associated edema, purpura, and progressive sloughing of [...]