Background: Mortality prediction models are increasingly being adopted in the clinical setting, both to retrospectively assess quality of care and to prospectively inform clinical practice. An open question is whether a particular hospital should employ a model trained using a diverse nationwide dataset or use a model developed primarily from local data. The Veterans Affairs [...]

Background: Diagnostic errors (DEs) represent ongoing threats to patient safety in the hospital. Little is known about the factors present on admission that can predict DE during the hospital encounter. Such knowledge is essential for prospective identification of hospitalized patients at risk for DE who can be targeted for early intervention. The purpose of this [...]

Background: Mortality prediction models are increasingly being adopted in the clinical setting, both to retrospectively assess quality of care and to prospectively inform clinical practice. An open question is whether a particular hospital should employ a model trained using a diverse nationwide dataset or use a model developed primarily from local data. The Veterans Affairs [...]

Background: Diagnostic errors (DEs) represent ongoing threats to patient safety in the hospital. Little is known about the factors present on admission that can predict DE during the hospital encounter. Such knowledge is essential for prospective identification of hospitalized patients at risk for DE who can be targeted for early intervention. The purpose of this [...]

Case Presentation: We present a 41-year-old female with a past medical history of hypertension and ESRD status post deceased donor kidney transplant in 2018, on treatment with tacrolimus and Mycophenolate Mofetil.She presented to an urgent care 4 days prior, where she tested positive for symptomatic COVID-19 infection and was prescribed a 5-day course of nirmatrelvir-ritonavir. [...]

Case Presentation: A 31-year-old man with past medical history of secondary syphilis and HIV/AIDS (CD4 47) intermittently on ART presented with worsening rectal pain and recurrent rectal abscesses. He endorsed rectal pruritis, nausea, weight loss, and lower extremity pain. He denied fevers, night sweats, abdominal pain, or diarrhea. Last year, he had a prior rectal [...]

Background: The American opioid epidemic is a public health emergency, with over 100,000 opioid-related overdose deaths occurring in 2021 (1). Harm reduction treatment models, formulated with the goal of reducing the negative consequences of opioid use, have been implemented as an alternative approach in minimizing opioid overdose and mortality (2). With approximately 4-11% of hospitalized [...]

Background: Alcohol use disorder (AUD) is the most prevalent substance use disorder, but most patients with AUD do not receive evidence-based medications for AUD (MAUD), including naltrexone or acamprosate. Inpatient addiction consult services (ACS) may offer an opportunity to start medical treatment for hospitalized patients with AUD, but it is unknown if ACS are associated [...]

Background: Anemia is a risk factor for cognitive impairment as a result of the reduced delivery of oxygen to the brain from low hemoglobin (Hb) levels. In ambulatory patients even mild anemia (Hb < 12g/dL) has been associated with reductions in patients’ cognitive function. However, in hospitalized patients it is standard of care to maintain [...]

Background: Accurate coding is paramount to hospital revenue generation and is often supported by a clinical documentation integrity (CDI) team made up of registered nurses and non-clinical coding personnel. Physician-led coding initiatives have demonstrated improvement in case-mix index and clinical documentation. We hypothesized that physician integration into CDI would result in a more robust improvement [...]